Ekasi uses both the printed medium and the radio to reach out to South African youth with entertaining yet information-rich messages related to HIV/AIDS. It consists of a monthly comic book and a weekly interactive radio talk show that airs on YFM (99.2 MHz), a youth radio station once a week.

Specifically, the eKasi comic book is a serialised story of Thandi, a young HIV-positive girl who becomes a co-host on a radio talk show after "breaking the silence" by telling her own story on the air. (In Issue 1, she shares her experience on air of having been raped by her uncle, explaining that she is now HIV-positive). Her revelation and ability to talk openly and honestly about her status lead to her being offered a regular show on the radio and to developing a substantial audience for her show. The next 23 issues introduce new characters like DJ Smooth, Brad who is also HIV positive, and other characters that surface occasionally in different contexts and other issues of the comic.

Sponsored by the Gauteng Department of Health, the comic was published each month and was distributed as a free supplement in South Africa's biggest daily newspaper, Daily Sun, as well as directly to 100 schools in Gauteng and to several partner non-governmental organisations (NGOs). These distribution channels gave eKasi a circulation of 180,000 copies per month.

Youth, HIV/AIDS, Health.

Organisers believe that reading will lead to learning and that learning, in turn, fosters behavioural change. "It at least puts the youth in touch with informed choices they can make to prevent the further spread of HIV/AIDS."